Ataxin1L Is a Regulator of HSC Function Highlighting the Utility of Cross-Tissue Comparisons for Gene Discovery

Hematopoietic stem cells (HSCs) are rare quiescent cells that continuously replenish the cellular components of the peripheral blood. Observing that the ataxia-associated gene Ataxin-1-like (Atxn1L) was highly expressed in HSCs, we examined its role in HSC function through in vitro and in vivo assay...

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Detalles Bibliográficos
Autores principales: Kahle, Juliette J., Souroullas, George P., Yu, Peng, Zohren, Fabian, Lee, Yoontae, Shaw, Chad A., Zoghbi, Huda Y., Goodell, Margaret A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3610904/
https://www.ncbi.nlm.nih.gov/pubmed/23555280
http://dx.doi.org/10.1371/journal.pgen.1003359

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3610904/
https://www.ncbi.nlm.nih.gov/pubmed/23555280
http://dx.doi.org/10.1371/journal.pgen.1003359

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