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Insulin-Like Growth Factor 1 (IGF-1) Enhances the Protein Expression of CFTR

Low levels of insulin-like growth factor 1 (IGF-1) have been observed in the serum of cystic fibrosis (CF) patients. However, the effects of low serum IGF-1 on the cystic fibrosis transmembrane conductance regulator (CFTR), whose defective function is the primary cause of cystic fibrosis, have not b...

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Detalles Bibliográficos
Autores principales: Lee, Ha Won, Cheng, Jie, Kovbasnjuk, Olga, Donowitz, Mark, Guggino, William B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3610909/
https://www.ncbi.nlm.nih.gov/pubmed/23555857
http://dx.doi.org/10.1371/journal.pone.0059992