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A Copy Number Variant at the KITLG Locus Likely Confers Risk for Canine Squamous Cell Carcinoma of the Digit

The domestic dog is a robust model for studying the genetics of complex disease susceptibility. The strategies used to develop and propagate modern breeds have resulted in an elevated risk for specific diseases in particular breeds. One example is that of Standard Poodles (STPOs), who have increased...

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Detalles Bibliográficos
Autores principales: Karyadi, Danielle M., Karlins, Eric, Decker, Brennan, vonHoldt, Bridgett M., Carpintero-Ramirez, Gretchen, Parker, Heidi G., Wayne, Robert K., Ostrander, Elaine A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3610924/
https://www.ncbi.nlm.nih.gov/pubmed/23555311
http://dx.doi.org/10.1371/journal.pgen.1003409