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Transcriptional Responses of In Vivo Praziquantel Exposure in Schistosomes Identifies a Functional Role for Calcium Signalling Pathway Member CamKII

Treatment for clinical schistosomiasis has relied centrally on the broad spectrum anthelmintic praziquantel; however, there is limited information on its mode of action or the molecular response of the parasite. This paper presents a transcriptional and functional approach to defining the molecular...

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Detalles Bibliográficos
Autores principales: You, Hong, McManus, Donald P., Hu, Wei, Smout, Michael J., Brindley, Paul J., Gobert, Geoffrey N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3610926/
https://www.ncbi.nlm.nih.gov/pubmed/23555262
http://dx.doi.org/10.1371/journal.ppat.1003254