Site Specific Mutation of the Zic2 Locus by Microinjection of TALEN mRNA in Mouse CD1, C3H and C57BL/6J Oocytes

Transcription Activator-Like Effector Nucleases (TALENs) consist of a nuclease domain fused to a DNA binding domain which is engineered to bind to any genomic sequence. These chimeric enzymes can be used to introduce a double strand break at a specific genomic site which then can become the substrat...

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Detalles Bibliográficos
Autores principales: Davies, Benjamin, Davies, Graham, Preece, Christopher, Puliyadi, Rathi, Szumska, Dorota, Bhattacharya, Shoumo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3610929/
https://www.ncbi.nlm.nih.gov/pubmed/23555929
http://dx.doi.org/10.1371/journal.pone.0060216

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3610929/
https://www.ncbi.nlm.nih.gov/pubmed/23555929
http://dx.doi.org/10.1371/journal.pone.0060216

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