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Frequent Engagement of RelB Activation Is Critical for Cell Survival in Multiple Myeloma

The NF-κB family of transcription factors has emerged as a key player in the pathogenesis of multiple myeloma (MM). NF-κB is activated by at least two major signaling pathways. The classical pathway results in the activation of mainly RelA containing dimers, whereas the alternative pathway leads to...

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Detalles Bibliográficos
Autores principales: Cormier, Françoise, Monjanel, Hélène, Fabre, Claire, Billot, Katy, Sapharikas, Elène, Chereau, Fanny, Bordereaux, Didier, Molina, Thierry J., Avet-Loiseau, Hervé, Baud, Véronique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3610937/
https://www.ncbi.nlm.nih.gov/pubmed/23555623
http://dx.doi.org/10.1371/journal.pone.0059127