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Functional activity of the cannabinoid 1 receptor is not affected by opioid antagonists in the rat brain
BACKGROUND: WIN55212-2 is a synthetic cannabinoid agonist and selective to cannabinoid 1 (CB1) receptors, which are distributed mainly in the central nervous system. Opioid receptors and CB1 receptors have several similarities in terms of their intracellular signal transduction mechanisms, distribut...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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The Korean Society of Anesthesiologists
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3611077/ https://www.ncbi.nlm.nih.gov/pubmed/23560193 http://dx.doi.org/10.4097/kjae.2013.64.3.257 |