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Prima-1 induces apoptosis in bladder cancer cell lines by activating p53

OBJECTIVES: Bladder cancer represents 3% of all carcinomas in the Brazilian population and ranks second in incidence among urological tumors, after prostate cancer. The loss of p53 function is the main genetic alteration related to the development of high-grade muscle-invasive disease. Prima-1 is a...

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Detalles Bibliográficos
Autores principales: Piantino, Camila B., Reis, Sabrina T., Viana, Nayara I., Silva, Iran A., Morais, Denis R., Antunes, Alberto A., Dip, Nelson, Srougi, Miguel, Leite, Katia R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3611750/
https://www.ncbi.nlm.nih.gov/pubmed/23644847
http://dx.doi.org/10.6061/clinics/2013(03)OA03