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A Novel Peptide Delivers Plasmids across Blood-Brain Barrier into Neuronal Cells as a Single-Component Transfer Vector

There is no data up to now to show that peptide can deliver plasmid into brain as a single-component transfer vector. Here we show that a novel peptide, RDP (consisted of 39 amino acids), can be exploited as an efficient plasmid vector for brain-targeting delivery. The plasmids containing Lac Z repo...

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Detalles Bibliográficos
Autores principales: Fu, Ailing, Zhang, Miaomiao, Gao, Feiyan, Xu, Xingran, Chen, Zhangbao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3612029/
https://www.ncbi.nlm.nih.gov/pubmed/23555734
http://dx.doi.org/10.1371/journal.pone.0059642