Non-Canonical CRL4A/4B(CDT2) Interacts with RAD18 to Modulate Post Replication Repair and Cell Survival

The Cullin-4(CDT2) E3 ubiquitin ligase plays an essential role in DNA replication origin licensing directing degradation of several licensing factors at the G1/S transition in order to prevent DNA re-replication. Recently a RAD18-independent role of Cullin-4(CDT2) in PCNA monoubiquitylation has been...

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Detalles Bibliográficos
Autores principales: Sertic, Sarah, Evolvi, Claudio, Tumini, Emanuela, Plevani, Paolo, Muzi-Falconi, Marco, Rotondo, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3612035/
https://www.ncbi.nlm.nih.gov/pubmed/23555860
http://dx.doi.org/10.1371/journal.pone.0060000

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3612035/
https://www.ncbi.nlm.nih.gov/pubmed/23555860
http://dx.doi.org/10.1371/journal.pone.0060000

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