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ERG Induces Epigenetic Activation of Tudor Domain-Containing Protein 1 (TDRD1) in ERG Rearrangement-Positive Prostate Cancer

BACKGROUND: Overexpression of ERG transcription factor due to genomic ERG-rearrangements defines a separate molecular subtype of prostate tumors. One of the consequences of ERG accumulation is modulation of the cell’s gene expression profile. Tudor domain-containing protein 1 gene (TDRD1) was report...

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Detalles Bibliográficos
Autores principales: Kacprzyk, Lukasz A., Laible, Mark, Andrasiuk, Tatjana, Brase, Jan C., Börno, Stefan T., Fälth, Maria, Kuner, Ruprecht, Lehrach, Hans, Schweiger, Michal R., Sültmann, Holger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3612037/
https://www.ncbi.nlm.nih.gov/pubmed/23555854
http://dx.doi.org/10.1371/journal.pone.0059976