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ERG Induces Epigenetic Activation of Tudor Domain-Containing Protein 1 (TDRD1) in ERG Rearrangement-Positive Prostate Cancer
BACKGROUND: Overexpression of ERG transcription factor due to genomic ERG-rearrangements defines a separate molecular subtype of prostate tumors. One of the consequences of ERG accumulation is modulation of the cell’s gene expression profile. Tudor domain-containing protein 1 gene (TDRD1) was report...
Autores principales: | Kacprzyk, Lukasz A., Laible, Mark, Andrasiuk, Tatjana, Brase, Jan C., Börno, Stefan T., Fälth, Maria, Kuner, Ruprecht, Lehrach, Hans, Schweiger, Michal R., Sültmann, Holger |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3612037/ https://www.ncbi.nlm.nih.gov/pubmed/23555854 http://dx.doi.org/10.1371/journal.pone.0059976 |
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