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Diesel Exhaust Particles Induce Cysteine Oxidation and S-Glutathionylation in House Dust Mite Induced Murine Asthma

BACKGROUND: Diesel exhaust particle (DEP) exposure enhances allergic inflammation and has been linked to the incidence of asthma. Oxidative stress on the thiol molecules cysteine (Cys) and glutathione (GSH) can promote inflammatory host responses. The effect of DEP on the thiol oxidation/reduction (...

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Detalles Bibliográficos
Autores principales: Lee, Gerald B., Brandt, Eric B., Xiao, Chang, Gibson, Aaron M., Le Cras, Timothy D., Brown, Lou Ann S., Fitzpatrick, Anne M., Khurana Hershey, Gurjit K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3612047/
https://www.ncbi.nlm.nih.gov/pubmed/23555996
http://dx.doi.org/10.1371/journal.pone.0060632