An Appraisal of Human Mitochondrial DNA Instability: New Insights into the Role of Non-Canonical DNA Structures and Sequence Motifs

Mitochondrial DNA (mtDNA) deletion mutations are frequently observed in aged postmitotic tissues and are the cause of a wide range of human disorders. Presently, the molecular bases underlying mtDNA deletion formation remain a matter of intense debate, and it is commonly accepted that several mechan...

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Detalles Bibliográficos
Autores principales: Oliveira, Pedro H., Lobato da Silva, Cláudia, Cabral, Joaquim M. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3612095/
https://www.ncbi.nlm.nih.gov/pubmed/23555828
http://dx.doi.org/10.1371/journal.pone.0059907

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3612095/
https://www.ncbi.nlm.nih.gov/pubmed/23555828
http://dx.doi.org/10.1371/journal.pone.0059907

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