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Pseudomonas aeruginosa Cytotoxicity Is Attenuated at High Cell Density and Associated with the Accumulation of Phenylacetic Acid

BACKGROUND: P. aeruginosa is known to cause acute cytotoxicity against various human and animal cells and tissues. METHODOLOGY/FINDINGS: Intriguingly, however, in this study we noticed that while a low cell density inoculum of P. aeruginosa caused severe cytotoxicity against human lung tissue cell l...

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Detalles Bibliográficos
Autores principales: Wang, Jianhe, Dong, Yihu, Zhou, Tielin, Liu, Xiaoling, Deng, Yinyue, Wang, Chao, Lee, Jasmine, Zhang, Lian-Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3612096/
https://www.ncbi.nlm.nih.gov/pubmed/23555919
http://dx.doi.org/10.1371/journal.pone.0060187