Understanding the Specificity of Human Galectin-8C Domain Interactions with Its Glycan Ligands Based on Molecular Dynamics Simulations

Human Galectin-8 (Gal-8) is a member of the galectin family which shares an affinity for β-galactosides. The tandem-repeat Gal-8 consists of a N- and a C-terminal carbohydrate recognition domain (N- and C-CRD) joined by a linker peptide of various length. Despite their structural similarity both CRD...

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Detalles Bibliográficos
Autores principales: Kumar, Sonu, Frank, Martin, Schwartz-Albiez, Reinhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3612102/
https://www.ncbi.nlm.nih.gov/pubmed/23555773
http://dx.doi.org/10.1371/journal.pone.0059761

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3612102/
https://www.ncbi.nlm.nih.gov/pubmed/23555773
http://dx.doi.org/10.1371/journal.pone.0059761

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