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Optimizing Treatment Regimes to Hinder Antiviral Resistance in Influenza across Time Scales
The large-scale use of antivirals during influenza pandemics poses a significant selection pressure for drug-resistant pathogens to emerge and spread in a population. This requires treatment strategies to minimize total infections as well as the emergence of resistance. Here we propose a mathematica...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3612110/ https://www.ncbi.nlm.nih.gov/pubmed/23555694 http://dx.doi.org/10.1371/journal.pone.0059529 |