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Optimizing Treatment Regimes to Hinder Antiviral Resistance in Influenza across Time Scales

The large-scale use of antivirals during influenza pandemics poses a significant selection pressure for drug-resistant pathogens to emerge and spread in a population. This requires treatment strategies to minimize total infections as well as the emergence of resistance. Here we propose a mathematica...

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Detalles Bibliográficos
Autores principales: Patterson-Lomba, Oscar, Althouse, Benjamin M., Goerg, Georg M., Hébert-Dufresne, Laurent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3612110/
https://www.ncbi.nlm.nih.gov/pubmed/23555694
http://dx.doi.org/10.1371/journal.pone.0059529