PI3K inhibition potentiates Bcl-2-dependent apoptosis in renal carcinoma cells

Inhibitors of PI3-K/Akt are currently being assessed clinically in patients with advanced RCC. Identification of therapeutic strategies that might enhance the efficacy of PI3-K/Akt inhibitors is therefore of great interest. As PI3-K inhibition would be expected to have many pro-apoptotic effects, we...

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Detalles Bibliográficos
Autores principales: Zhu, Shudong, Cohen, Matthew B, Bjorge, Jeffrey D, Mier, James W, Cho, Daniel C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3612143/
https://www.ncbi.nlm.nih.gov/pubmed/23387989
http://dx.doi.org/10.1111/jcmm.12019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3612143/
https://www.ncbi.nlm.nih.gov/pubmed/23387989
http://dx.doi.org/10.1111/jcmm.12019

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