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In-silico designing of a potent analogue against HIV-1 Nef protein and protease by predicting its interaction network with host cell proteins

BACKGROUND: HIV-1 has numerous proteins encoded within its genome, which acquaints it with the required arsenal to establish a favorable host cell environment suitable for viral replication and pathogenesis. Among these proteins, one protein that is indispensable and ambiguous is the Nef protein. AI...

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Detalles Bibliográficos
Autores principales: Pal, Shikha, Mishra, Madhur, Sudhakar, D. Raja, Siddiqui, Mohammed Haris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3612342/
https://www.ncbi.nlm.nih.gov/pubmed/23559827
http://dx.doi.org/10.4103/0975-7406.106572