Development and validation of an improved LC-MS/MS method for the quantification of desloratadine and its metabolite in human plasma using deutrated desloratadine as internal standard

PURPOSE: For the determination of desloratadine (DES) and 3-OH desloratadine (3-OHD) in human plasma using deutrated desloratadine (DESD5) as internal standard (IS), a novel stability indicating liquid chromatography-tandem mass spectrometric method was developed and validated to support the clinica...

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Detalles Bibliográficos
Autores principales: Hasnain, M. Saquib, Rao, Shireen, Singh, Manoj Kr., Vig, Nitin, Singh, Manish Kr., Budakoti, Subodh Kr., Ansari, Abdulla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3612343/
https://www.ncbi.nlm.nih.gov/pubmed/23559828
http://dx.doi.org/10.4103/0975-7406.106571

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3612343/
https://www.ncbi.nlm.nih.gov/pubmed/23559828
http://dx.doi.org/10.4103/0975-7406.106571

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