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Development and validation of an improved LC-MS/MS method for the quantification of desloratadine and its metabolite in human plasma using deutrated desloratadine as internal standard
PURPOSE: For the determination of desloratadine (DES) and 3-OH desloratadine (3-OHD) in human plasma using deutrated desloratadine (DESD5) as internal standard (IS), a novel stability indicating liquid chromatography-tandem mass spectrometric method was developed and validated to support the clinica...
Autores principales: | Hasnain, M. Saquib, Rao, Shireen, Singh, Manoj Kr., Vig, Nitin, Singh, Manish Kr., Budakoti, Subodh Kr., Ansari, Abdulla |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3612343/ https://www.ncbi.nlm.nih.gov/pubmed/23559828 http://dx.doi.org/10.4103/0975-7406.106571 |
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