Adrenocorticotropic hormone ameliorates acute kidney injury by steroidogenic-dependent and -independent mechanisms

Adrenocorticotropic hormone (ACTH) has a renoprotective effect in chronic kidney disease; however, its effect on acute kidney injury (AKI) remains unknown. In a rat model of tumor necrosis factor (TNF)–induced AKI, we found that ACTH gel prevented kidney injury, corrected acute renal dysfunction, an...

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Detalles Bibliográficos
Autores principales: Si, Jin, Ge, Yan, Zhuang, Shougang, Juan Wang, Li, Chen, Shan, Gong, Rujun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Basic Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3612362/
https://www.ncbi.nlm.nih.gov/pubmed/23325074
http://dx.doi.org/10.1038/ki.2012.447

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3612362/
https://www.ncbi.nlm.nih.gov/pubmed/23325074
http://dx.doi.org/10.1038/ki.2012.447

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