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Predicting the molecular complexity of sequencing libraries

Predicting the molecular complexity of a genomic sequencing library has emerged as a critical but difficult problem in modern applications of genome sequencing. Available methods to determine either how deeply to sequence, or predict the benefits of additional sequencing, are almost completely lacki...

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Detalles Bibliográficos
Autores principales: Daley, Timothy, Smith, Andrew D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3612374/
https://www.ncbi.nlm.nih.gov/pubmed/23435259
http://dx.doi.org/10.1038/nmeth.2375