Neutron-encoded mass signatures for multi-plexed proteome quantification

We describe a protein quantification method that exploits the subtle mass differences caused by neutron-binding energy variation in stable isotopes. These mass differences are synthetically encoded into amino acids and incorporated into yeast and mouse proteins with metabolic labeling; analysis with...

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Detalles Bibliográficos
Autores principales: Hebert, Alexander S, Merrill, Anna E, Bailey, Derek J, Still, Amelia J, Westphall, Michael S, Streiter, Eric R, Pagliarini, David J, Coon, Joshua J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3612390/
https://www.ncbi.nlm.nih.gov/pubmed/23435260
http://dx.doi.org/10.1038/nmeth.2378

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3612390/
https://www.ncbi.nlm.nih.gov/pubmed/23435260
http://dx.doi.org/10.1038/nmeth.2378

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