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Neutron-encoded mass signatures for multi-plexed proteome quantification
We describe a protein quantification method that exploits the subtle mass differences caused by neutron-binding energy variation in stable isotopes. These mass differences are synthetically encoded into amino acids and incorporated into yeast and mouse proteins with metabolic labeling; analysis with...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3612390/ https://www.ncbi.nlm.nih.gov/pubmed/23435260 http://dx.doi.org/10.1038/nmeth.2378 |