Insertion mutants in Drosophila melanogaster Hsc20 halt larval growth and lead to reduced iron–sulfur cluster enzyme activities and impaired iron homeostasis

Despite the prominence of iron–sulfur cluster (ISC) proteins in bioenergetics, intermediary metabolism, and redox regulation of cellular, mitochondrial, and nuclear processes, these proteins have been given scarce attention in Drosophila. Moreover, biosynthesis and delivery of ISCs to target protein...

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Detalles Bibliográficos
Autores principales: Uhrigshardt, Helge, Rouault, Tracey A., Missirlis, Fanis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2013
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3612401/
https://www.ncbi.nlm.nih.gov/pubmed/23444034
http://dx.doi.org/10.1007/s00775-013-0988-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3612401/
https://www.ncbi.nlm.nih.gov/pubmed/23444034
http://dx.doi.org/10.1007/s00775-013-0988-2

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