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The role of apolipoprotein E (APOE) genotype in early mild cognitive impairment (E-MCI)

Objective: Our goal was to evaluate the association of APOE with amyloid deposition, cerebrospinal fluid levels (CSF) of Aβ, tau, and p-tau, brain atrophy, cognition and cognitive complaints in E-MCI patients and cognitively healthy older adults (HC) in the ADNI-2 cohort. Methods: Two-hundred and ni...

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Detalles Bibliográficos
Autores principales: Risacher, Shannon L., Kim, Sungeun, Shen, Li, Nho, Kwangsik, Foroud, Tatiana, Green, Robert C., Petersen, Ronald C., Jack, Clifford R., Aisen, Paul S., Koeppe, Robert A., Jagust, William J., Shaw, Leslie M., Trojanowski, John Q., Weiner, Michael W., Saykin, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3612590/
https://www.ncbi.nlm.nih.gov/pubmed/23554593
http://dx.doi.org/10.3389/fnagi.2013.00011