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The role of apolipoprotein E (APOE) genotype in early mild cognitive impairment (E-MCI)
Objective: Our goal was to evaluate the association of APOE with amyloid deposition, cerebrospinal fluid levels (CSF) of Aβ, tau, and p-tau, brain atrophy, cognition and cognitive complaints in E-MCI patients and cognitively healthy older adults (HC) in the ADNI-2 cohort. Methods: Two-hundred and ni...
Autores principales: | Risacher, Shannon L., Kim, Sungeun, Shen, Li, Nho, Kwangsik, Foroud, Tatiana, Green, Robert C., Petersen, Ronald C., Jack, Clifford R., Aisen, Paul S., Koeppe, Robert A., Jagust, William J., Shaw, Leslie M., Trojanowski, John Q., Weiner, Michael W., Saykin, Andrew J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3612590/ https://www.ncbi.nlm.nih.gov/pubmed/23554593 http://dx.doi.org/10.3389/fnagi.2013.00011 |
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