Study protocol for a randomised controlled double-blinded trial of the dose-dependent efficacy and safety of primaquine for clearance of gametocytes in children with uncomplicated falciparum malaria in Uganda

OBJECTIVES: For the purpose of blocking transmission of Plasmodium falciparum malaria from humans to mosquitoes, a single dose of primaquine is recommended by the WHO as an addition to artemisinin combination therapy. Primaquine clears gametocytes but causes dose-dependent haemolysis in individuals...

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Detalles Bibliográficos
Autores principales: Eziefula, Alice Chijioke, Staedke, Sarah G, Yeung, Shunmay, Webb, Emily, Kamya, Moses, White, Nicholas J, Bousema, Teun, Drakeley, Chris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2013
Materias:
Infectious Diseases
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3612795/
https://www.ncbi.nlm.nih.gov/pubmed/23535703
http://dx.doi.org/10.1136/bmjopen-2013-002759

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3612795/
https://www.ncbi.nlm.nih.gov/pubmed/23535703
http://dx.doi.org/10.1136/bmjopen-2013-002759

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