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Structural-Functional Analysis of 2,1,3-Benzoxadiazoles and Their N-oxides As HIV-1 Integrase Inhibitors

Human immunodeficiency virus type 1 integrase is one of the most attractive targets for the development of anti-HIV-1 inhibitors. The capacity of a series of 2,1,3-benzoxadiazoles (benzofurazans) and their N-oxides (benzofuroxans) selected using the PASS software to inhibit the catalytic activity of...

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Detalles Bibliográficos
Autores principales: Korolev, S. P., Kondrashina, O. V., Druzhilovsky, D. S., Starosotnikov, A. M., Dutov, M. D., Bastrakov, M. A., Dalinger, I. L., Filimonov, D. A., Shevelev, S. A., Poroikov, V. V., Agapkina, Y. Y., Gottikh, M. B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: A.I. Gordeyev 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3612826/
https://www.ncbi.nlm.nih.gov/pubmed/23556131