Get3 is a holdase chaperone and moves to deposition sites for aggregated proteins when membrane targeting is blocked

The endomembrane system of yeast contains different tail-anchored proteins that are post-translationally targeted to membranes via their C-terminal transmembrane domain. This hydrophobic segment could be hazardous in the cytosol if membrane insertion fails, resulting in the need for energy-dependent...

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Detalles Bibliográficos
Autores principales: Powis, Katie, Schrul, Bianca, Tienson, Heather, Gostimskaya, Irina, Breker, Michal, High, Stephen, Schuldiner, Maya, Jakob, Ursula, Schwappach, Blanche
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3613179/
https://www.ncbi.nlm.nih.gov/pubmed/23203805
http://dx.doi.org/10.1242/jcs.112151

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3613179/
https://www.ncbi.nlm.nih.gov/pubmed/23203805
http://dx.doi.org/10.1242/jcs.112151

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