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Mycobacterium tuberculosis ClpP Proteases Are Co-transcribed but Exhibit Different Substrate Specificities

Caseinolytic (Clp) proteases are widespread energy-dependent proteases; the functional ATP-dependent protease is comprised of multimers of proteolytic and regulatory subunits. Mycobacterium tuberculosis has two ClpP proteolytic subunits (ClpP1 and ClpP2), with both being essential for growth in vitr...

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Detalles Bibliográficos
Autores principales: Personne, Yoann, Brown, Amanda C., Schuessler, Dorothée L., Parish, Tanya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3613350/
https://www.ncbi.nlm.nih.gov/pubmed/23560081
http://dx.doi.org/10.1371/journal.pone.0060228