Neuroinflammation and Neuronal Loss Precede Aβ Plaque Deposition in the hAPP-J20 Mouse Model of Alzheimer’s Disease

Recent human trials of treatments for Alzheimer’s disease (AD) have been largely unsuccessful, raising the idea that treatment may need to be started earlier in the disease, well before cognitive symptoms appear. An early marker of AD pathology is therefore needed and it is debated as to whether amy...

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Detalles Bibliográficos
Autores principales: Wright, Amanda L., Zinn, Raphael, Hohensinn, Barbara, Konen, Lyndsey M., Beynon, Sarah B., Tan, Richard P., Clark, Ian A., Abdipranoto, Andrea, Vissel, Bryce
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3613362/
https://www.ncbi.nlm.nih.gov/pubmed/23560052
http://dx.doi.org/10.1371/journal.pone.0059586

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3613362/
https://www.ncbi.nlm.nih.gov/pubmed/23560052
http://dx.doi.org/10.1371/journal.pone.0059586

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