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GSE Is a Maternal Factor Involved in Active DNA Demethylation in Zygotes

After fertilization, the sperm and oocyte genomes undergo extensive epigenetic reprogramming to form a totipotent zygote. The dynamic epigenetic changes during early embryo development primarily involve DNA methylation and demethylation. We have previously identified Gse (gonad-specific expression g...

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Detalles Bibliográficos
Autores principales: Hatanaka, Yuki, Shimizu, Natsumi, Nishikawa, Satoshi, Tokoro, Mikiko, Shin, Seung-Wook, Nishihara, Takuji, Amano, Tomoko, Anzai, Masayuki, Kato, Hiromi, Mitani, Tasuku, Hosoi, Yoshihiko, Kishigami, Satoshi, Matsumoto, Kazuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3613368/
https://www.ncbi.nlm.nih.gov/pubmed/23560077
http://dx.doi.org/10.1371/journal.pone.0060205