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Quantitative Design of Regulatory Elements Based on High-Precision Strength Prediction Using Artificial Neural Network
Accurate and controllable regulatory elements such as promoters and ribosome binding sites (RBSs) are indispensable tools to quantitatively regulate gene expression for rational pathway engineering. Therefore, de novo designing regulatory elements is brought back to the forefront of synthetic biolog...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3613377/ https://www.ncbi.nlm.nih.gov/pubmed/23560087 http://dx.doi.org/10.1371/journal.pone.0060288 |