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Quantitative Design of Regulatory Elements Based on High-Precision Strength Prediction Using Artificial Neural Network

Accurate and controllable regulatory elements such as promoters and ribosome binding sites (RBSs) are indispensable tools to quantitatively regulate gene expression for rational pathway engineering. Therefore, de novo designing regulatory elements is brought back to the forefront of synthetic biolog...

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Detalles Bibliográficos
Autores principales: Meng, Hailin, Wang, Jianfeng, Xiong, Zhiqiang, Xu, Feng, Zhao, Guoping, Wang, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3613377/
https://www.ncbi.nlm.nih.gov/pubmed/23560087
http://dx.doi.org/10.1371/journal.pone.0060288