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Transforming Growth Factor β(1) Induces the Expression of Collagen Type I by DNA Methylation in Cardiac Fibroblasts
Transforming growth factor-beta (TGF-β), a key mediator of cardiac fibroblast activation, has a major influence on collagen type I production. However, the epigenetic mechanisms by which TGF-β induces collagen type I alpha 1 (COL1A1) expression are not fully understood. This study was designed to ex...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3613378/ https://www.ncbi.nlm.nih.gov/pubmed/23560091 http://dx.doi.org/10.1371/journal.pone.0060335 |