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Transforming Growth Factor β(1) Induces the Expression of Collagen Type I by DNA Methylation in Cardiac Fibroblasts

Transforming growth factor-beta (TGF-β), a key mediator of cardiac fibroblast activation, has a major influence on collagen type I production. However, the epigenetic mechanisms by which TGF-β induces collagen type I alpha 1 (COL1A1) expression are not fully understood. This study was designed to ex...

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Detalles Bibliográficos
Autores principales:	Pan, Xiaodong, Chen, Zhongpu, Huang, Rong, Yao, Yuyu, Ma, Genshan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3613378/ https://www.ncbi.nlm.nih.gov/pubmed/23560091 http://dx.doi.org/10.1371/journal.pone.0060335

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