Endocardial to Myocardial Notch-Wnt-Bmp Axis Regulates Early Heart Valve Development

Endocardial to mesenchymal transformation (EMT) is a fundamental cellular process required for heart valve formation. Notch, Wnt and Bmp pathways are known to regulate this process. To further address how these pathways coordinate in the process, we specifically disrupted Notch1 or Jagged1 in the en...

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Detalles Bibliográficos
Autores principales: Wang, Yidong, Wu, Bingruo, Chamberlain, Alyssa A., Lui, Wendy, Koirala, Pratistha, Susztak, Katalin, Klein, Diana, Taylor, Verdon, Zhou, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3613384/
https://www.ncbi.nlm.nih.gov/pubmed/23560082
http://dx.doi.org/10.1371/journal.pone.0060244

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3613384/
https://www.ncbi.nlm.nih.gov/pubmed/23560082
http://dx.doi.org/10.1371/journal.pone.0060244

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