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Endocardial to Myocardial Notch-Wnt-Bmp Axis Regulates Early Heart Valve Development
Endocardial to mesenchymal transformation (EMT) is a fundamental cellular process required for heart valve formation. Notch, Wnt and Bmp pathways are known to regulate this process. To further address how these pathways coordinate in the process, we specifically disrupted Notch1 or Jagged1 in the en...
Autores principales: | Wang, Yidong, Wu, Bingruo, Chamberlain, Alyssa A., Lui, Wendy, Koirala, Pratistha, Susztak, Katalin, Klein, Diana, Taylor, Verdon, Zhou, Bin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3613384/ https://www.ncbi.nlm.nih.gov/pubmed/23560082 http://dx.doi.org/10.1371/journal.pone.0060244 |
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