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Two 4N Cell-Cycle Arrests Contribute to Cisplatin-Resistance

Cisplatin is a platinum-based drug that is used for the treatment of a wide-variety of primary human cancers. However, the therapeutic efficacy of cisplatin is often limited by intrinsic or acquired drug resistance. An important goal, therefore, is to identify mechanisms that lead to cisplatin resis...

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Detalles Bibliográficos
Autores principales: Shen, Hong, Perez, Ricardo E., Davaadelger, Batzaya, Maki, Carl G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3613405/
https://www.ncbi.nlm.nih.gov/pubmed/23560058
http://dx.doi.org/10.1371/journal.pone.0059848