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Few Single Nucleotide Variations in Exomes of Human Cord Blood Induced Pluripotent Stem Cells

The effect of the cellular reprogramming process per se on mutation load remains unclear. To address this issue, we performed whole exome sequencing analysis of induced pluripotent stem cells (iPSCs) reprogrammed from human cord blood (CB) CD34(+) cells. Cells from a single donor and improved lentiv...

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Detalles Bibliográficos
Autores principales: Su, Rui-Jun, Yang, Yadong, Neises, Amanda, Payne, Kimberly J., Wang, Jasmin, Viswanathan, Kasthuribai, Wakeland, Edward K., Fang, Xiangdong, Zhang, Xiao-Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3613421/
https://www.ncbi.nlm.nih.gov/pubmed/23573220
http://dx.doi.org/10.1371/journal.pone.0059908