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Few Single Nucleotide Variations in Exomes of Human Cord Blood Induced Pluripotent Stem Cells
The effect of the cellular reprogramming process per se on mutation load remains unclear. To address this issue, we performed whole exome sequencing analysis of induced pluripotent stem cells (iPSCs) reprogrammed from human cord blood (CB) CD34(+) cells. Cells from a single donor and improved lentiv...
Autores principales: | Su, Rui-Jun, Yang, Yadong, Neises, Amanda, Payne, Kimberly J., Wang, Jasmin, Viswanathan, Kasthuribai, Wakeland, Edward K., Fang, Xiangdong, Zhang, Xiao-Bing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3613421/ https://www.ncbi.nlm.nih.gov/pubmed/23573220 http://dx.doi.org/10.1371/journal.pone.0059908 |
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