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A genome-wide RNA interference screen identifies new regulators of androgen receptor function in prostate cancer cells

The androgen receptor (AR) is a mediator of both androgen-dependent and castration-resistant prostate cancers. Identification of cellular factors affecting AR transcriptional activity could in principle yield new targets that reduce AR activity and combat prostate cancer, yet a comprehensive analysi...

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Detalles Bibliográficos
Autores principales: Imberg-Kazdan, Keren, Ha, Susan, Greenfield, Alex, Poultney, Christopher S., Bonneau, Richard, Logan, Susan K., Garabedian, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3613576/
https://www.ncbi.nlm.nih.gov/pubmed/23403032
http://dx.doi.org/10.1101/gr.144774.112