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Analysis of CDS-located miRNA target sites suggests that they can effectively inhibit translation

Most of what is presently known about how miRNAs regulate gene expression comes from studies that characterized the regulatory effect of miRNA binding sites located in the 3′ untranslated regions (UTR) of mRNAs. In recent years, there has been increasing evidence that miRNAs also bind in the coding...

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Detalles Bibliográficos
Autores principales: Hausser, Jean, Syed, Afzal Pasha, Bilen, Biter, Zavolan, Mihaela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3613578/
https://www.ncbi.nlm.nih.gov/pubmed/23335364
http://dx.doi.org/10.1101/gr.139758.112