RNA-seq–based mapping and candidate identification of mutations from forward genetic screens

Forward genetic screens have elucidated molecular pathways required for innumerable aspects of life; however, identifying the causal mutations from such screens has long been the bottleneck in the process, particularly in vertebrates. We have developed an RNA-seq–based approach that identifies both...

Descripción completa

Detalles Bibliográficos
Autores principales: Miller, Adam C., Obholzer, Nikolaus D., Shah, Arish N., Megason, Sean G., Moens, Cecilia B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2013
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3613584/
https://www.ncbi.nlm.nih.gov/pubmed/23299976
http://dx.doi.org/10.1101/gr.147322.112

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3613584/
https://www.ncbi.nlm.nih.gov/pubmed/23299976
http://dx.doi.org/10.1101/gr.147322.112

Ejemplares similares