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Global analysis of SUMO chain function reveals multiple roles in chromatin regulation

Like ubiquitin, the small ubiquitin-related modifier (SUMO) proteins can form oligomeric “chains,” but the biological functions of these superstructures are not well understood. Here, we created mutant yeast strains unable to synthesize SUMO chains (smt3(allR)) and subjected them to high-content mic...

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Detalles Bibliográficos
Autores principales: Srikumar, Tharan, Lewicki, Megan C., Costanzo, Michael, Tkach, Johnny M., van Bakel, Harm, Tsui, Kyle, Johnson, Erica S., Brown, Grant W., Andrews, Brenda J., Boone, Charles, Giaever, Guri, Nislow, Corey, Raught, Brian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3613684/
https://www.ncbi.nlm.nih.gov/pubmed/23547032
http://dx.doi.org/10.1083/jcb.201210019