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Global analysis of SUMO chain function reveals multiple roles in chromatin regulation
Like ubiquitin, the small ubiquitin-related modifier (SUMO) proteins can form oligomeric “chains,” but the biological functions of these superstructures are not well understood. Here, we created mutant yeast strains unable to synthesize SUMO chains (smt3(allR)) and subjected them to high-content mic...
Autores principales: | Srikumar, Tharan, Lewicki, Megan C., Costanzo, Michael, Tkach, Johnny M., van Bakel, Harm, Tsui, Kyle, Johnson, Erica S., Brown, Grant W., Andrews, Brenda J., Boone, Charles, Giaever, Guri, Nislow, Corey, Raught, Brian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3613684/ https://www.ncbi.nlm.nih.gov/pubmed/23547032 http://dx.doi.org/10.1083/jcb.201210019 |
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