γ-Catenin is overexpressed in acute myeloid leukemia and promotes the stabilization and nuclear localization of β-catenin

Canonical Wnt signaling regulates the transcription of T-cell factor (TCF)-responsive genes through the stabilization and nuclear translocation of the transcriptional co-activator, β-catenin. Overexpression of β-catenin features prominently in acute myeloid leukemia (AML) and has previously been ass...

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Detalles Bibliográficos
Autores principales: Morgan, R G, Pearn, L, Liddiard, K, Pumford, S L, Burnett, A K, Tonks, A, Darley, R L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3613703/
https://www.ncbi.nlm.nih.gov/pubmed/22858986
http://dx.doi.org/10.1038/leu.2012.221

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3613703/
https://www.ncbi.nlm.nih.gov/pubmed/22858986
http://dx.doi.org/10.1038/leu.2012.221

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