Overexpression of the mTERT gene by adenoviral vectors promotes the proliferation of neuronal stem cells in vitro and stimulates neurogenesis in the hippocampus of mice

We sought to construct the adenoviral vector carrying the gene encoding mouse telomerase reverse transcriptase (mTERT), as well as detect its expression and effect on the proliferation of neuronal stem cells. mTERT was amplified by RT-PCR and then the eukaryotic expression vector of pDC-EGFP-TERT wa...

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Detalles Bibliográficos
Autores principales: Liu, Mengying, Hu, Yao, Zhu, Lijuan, Chen, Chen, Zhang, Yu, Sun, Weixiang, Zhou, Qigang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Editorial Department of Journal of Biomedical Research 2012
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3613735/
https://www.ncbi.nlm.nih.gov/pubmed/23554775
http://dx.doi.org/10.7555/JBR.26.20110078

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3613735/
https://www.ncbi.nlm.nih.gov/pubmed/23554775
http://dx.doi.org/10.7555/JBR.26.20110078

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