Cargando…

Overexpression of the mTERT gene by adenoviral vectors promotes the proliferation of neuronal stem cells in vitro and stimulates neurogenesis in the hippocampus of mice

We sought to construct the adenoviral vector carrying the gene encoding mouse telomerase reverse transcriptase (mTERT), as well as detect its expression and effect on the proliferation of neuronal stem cells. mTERT was amplified by RT-PCR and then the eukaryotic expression vector of pDC-EGFP-TERT wa...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Mengying, Hu, Yao, Zhu, Lijuan, Chen, Chen, Zhang, Yu, Sun, Weixiang, Zhou, Qigang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Editorial Department of Journal of Biomedical Research 2012
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3613735/ https://www.ncbi.nlm.nih.gov/pubmed/23554775 http://dx.doi.org/10.7555/JBR.26.20110078

Ejemplares similares

The proximal promoter region of mTert is sufficient to regulate telomerase activity in ES cells and transgenic animals
por: Pericuesta, Eva, et al.
Publicado: (2006)

Zinc finger protein 637 protects cells against oxidative stress-induced premature senescence by mTERT-mediated telomerase activity and telomere maintenance
por: Gao, B, et al.
Publicado: (2014)

Andrographolide Stimulates Neurogenesis in the Adult Hippocampus
por: Varela-Nallar, Lorena, et al.
Publicado: (2015)

Comparing effects of mTR and mTERT deletion on gene expression and DNA damage response: a critical examination of telomere length maintenance-independent roles of telomerase
por: Vidal-Cardenas, Sofia L., et al.
Publicado: (2010)

Construction and application of adenoviral vectors
por: Zhang, Hongbo, et al.
Publicado: (2023)

Targeted adenoviral vectors
por: Vigne, E, et al.
Publicado: (2001)

Xenogenic Adenoviral Vectors
por: Mittal, Suresh K., et al.
Publicado: (2016)

Xenogenic Adenoviral Vectors
por: Both, Gerald W.
Publicado: (2002)

Editorial: Adenoviral Infection and Immunity, and Adenoviral Vectors for Gene Therapy Applications
por: Zhang, Qiwei, et al.
Publicado: (2022)

ADENOVIRAL VECTORS FOR PROTEIN EXPRESSION
por: Von Seggern, Dan J., et al.
Publicado: (1999)

Revisiting adult neurogenesis and the role of erythropoietin for neuronal and oligodendroglial differentiation in the hippocampus
por: Hassouna, I, et al.
Publicado: (2016)

COVID-19 causes neuronal degeneration and reduces neurogenesis in human hippocampus
por: Bayat, Amir-Hossein, et al.
Publicado: (2022)

Retrograde adenoviral vector targeting of nociresponsive pontospinal noradrenergic neurons in the rat in vivo
por: Howorth, Patrick W, et al.
Publicado: (2009)

Androgens and Adult Neurogenesis in the Hippocampus
por: Blankers, Samantha A., et al.
Publicado: (2021)

Adult neurogenesis in the primate hippocampus
por: Li, Ye, et al.
Publicado: (2023)

Adenoviral Vectors for Hemophilia Gene Therapy
por: Brunetti-Pierri, N, et al.
Publicado: (2013)

The Role of Chromatin in Adenoviral Vector Function
por: Wong, Carmen M., et al.
Publicado: (2013)

Use of adenoviral vectors as veterinary vaccines
por: Ferreira, T B, et al.
Publicado: (2005)

Immunology of Adenoviral Vectors in Cancer Therapy
por: Shaw, Amanda Rosewell, et al.
Publicado: (2019)

Adenoviral Vector Vaccines Antigen Transgene
por: Ertl, Hildegund C.J.
Publicado: (2016)

Advances and Future Challenges in Adenoviral Vector Pharmacology and Targeting
por: Khare, Reeti, et al.
Publicado: (2011)

Using Multivalent Adenoviral Vectors for HIV Vaccination
por: Gu, Linlin, et al.
Publicado: (2013)

An Adenoviral Vector Based Vaccine for Rhodococcus equi
por: Giles, Carla, et al.
Publicado: (2016)

Chimpanzee adenoviral vectors as vaccines for outbreak pathogens
por: Ewer, Katie, et al.
Publicado: (2017)

Immunogenicity and Cross-Reactivity of Rhesus Adenoviral Vectors
por: Iampietro, M. Justin, et al.
Publicado: (2018)

Expanding the Spectrum of Adenoviral Vectors for Cancer Therapy
por: Gao, Jian, et al.
Publicado: (2020)

Targeted Adenoviral Vectors I: Transductional Targeting
por: Dmitriev, Igor P., et al.
Publicado: (2016)

Engineering Adenoviral Vectors with Improved GBM Selectivity
por: Bates, Emily A., et al.
Publicado: (2023)

The dynamics of adult neurogenesis in human hippocampus
por: Ihunwo, Amadi O., et al.
Publicado: (2016)

Functional neurogenesis in the adult hippocampus: then and now
por: Vadodaria, Krishna C., et al.
Publicado: (2014)

Plasticity in the Hippocampus, Neurogenesis and Drugs of Abuse
por: Avchalumov, Yosef, et al.
Publicado: (2021)

Age-Dependent Neurogenesis and Neuron Numbers within the Olfactory Bulb and Hippocampus of Homing Pigeons
por: Meskenaite, Virginia, et al.
Publicado: (2016)

Jiaweisinisan facilitates neurogenesis in the hippocampus after stress damage☆
por: Wu, Lili, et al.
Publicado: (2013)

Reactivation of Tert in the medial prefrontal cortex and hippocampus rescues aggression and depression of Tert(−/−) mice
por: Zhou, Q-G, et al.
Publicado: (2016)

Rescue of chimeric adenoviral vectors to expand the serotype repertoire
por: Roy, Soumitra, et al.
Publicado: (2007)

Distribution of adenoviral vector in brain after intravenous administration.
por: Moon, Chanil, et al.
Publicado: (2003)

Retargeting Adenoviral Vectors to Improve Gene Transfer into Tumors
por: Hogg, Richard T., et al.
Publicado: (2010)

Efficacy of an Adenoviral Vectored Multivalent Centralized Influenza Vaccine
por: Lingel, Amy, et al.
Publicado: (2017)

Rapid Cloning of Novel Rhesus Adenoviral Vaccine Vectors
por: Abbink, Peter, et al.
Publicado: (2018)

Danio Rerio as Model Organism for Adenoviral Vector Evaluation
por: Gulías, Paola, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_i0h5ni1a7g8c6hjaljueilpm25